Six Researchers.
One Database.

Author of "Lifespan: Why We Age and Why We Don't Have To." Sinclair's Information Theory of Aging proposes that aging is primarily a loss of epigenetic information, not DNA damage — and that sirtuins, activated by NAD+ and caloric restriction, can partially restore it. He's been taking 1g NMN + 1g resveratrol daily since the early 2010s and has publicly tracked his biological age markers over time.

Host of the Huberman Lab podcast (one of the most downloaded science podcasts globally). Huberman specializes in translating neuroscience into practical protocols — sleep, light, testosterone, stress, and recovery. His foundational insight: the first 30 minutes after waking set the neuroendocrine context for your entire day, and most people completely waste it on their phone.

Former actuarial scientist who spent 20 years predicting time of death for life insurance companies — and realized he could predict health outcomes by reading bloodwork. Now applies that framework to optimization. His primary focus: genetic variants (especially MTHFR), methylation, grounding, and breathwork. Famous for saying "your genes are not your destiny — but your methylation determines how they're expressed."

PhD in biomedical science, trained at St. Jude Children's Research Hospital. The most academically rigorous of the major biohacking voices — she reads primary literature and challenges popular claims when the data doesn't support them. Focus areas: sulforaphane and Nrf2, omega-3 index, vitamin D, sauna, and micronutrient optimization. Hosted by every major podcaster in the space for her ability to explain mechanisms without dumbing them down.

Medical Director at Cleveland Clinic Center for Functional Medicine and author of multiple New York Times #1 bestsellers including "Young Forever." Hyman's framework (UltraWellness / Functional Medicine) treats the body as an interconnected system — gut, hormones, inflammation, mitochondria, and detoxification — and uses root-cause diagnosis rather than symptom suppression. He's been outspoken about food as medicine long before it was mainstream.

35 years of research, 700+ published papers, director of the St. Petersburg Institute of Bioregulation and Gerontology. Khavinson developed the concept of peptide bioregulators — short peptides (2-4 amino acids) extracted from specific tissues that act as tissue-specific epigenetic regulators, normalizing gene expression in aging cells toward youthful patterns. His work is largely unknown in Western biohacking circles but is decades ahead of most anti-aging research in terms of human clinical data.